Systemic Infectious

A 65-year-old man presents with fever 39°C, hypotension (BP 80/50), tachycardia (HR 120), and confusion. Lactate 4 mmol/L. Suspected septic shock. The MOST appropriate initial management within 1 hour is:

In a confirmed acute systemic inflammatory response to streptococcal infection (Strep TSS — pyrogenic exotoxins), the MOST appropriate management is:

An infant presents with paroxysmal cough, post-tussive emesis, and inspiratory whoop. PCR positive for Bordetella pertussis. The MOST appropriate management is:

A healthcare worker sustains a hollow-bore needlestick injury from a known HIV-positive patient (viral load detectable). The MOST appropriate next step is:

Hepatitis B vaccine post-exposure for a healthcare worker with documented anti-HBs ≥10 IU/L on previous testing — the MOST appropriate approach is:

An Indigenous patient from a remote NT community presents with chronic suppurative skin lesions; PCR confirms Mycobacterium ulcerans (Bairnsdale ulcer). The MOST appropriate management is: